Elizabeth M Berry-Kravis Selected Research

BPN14770

1/2021

Inhibition of phosphodiesterase-4D in adults with fragile X syndrome: a randomized, placebo-controlled, phase 2 clinical trial.

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Elizabeth M Berry-Kravis Research Topics

Disease

12	Sudden Infant Death (SID) 12/2013 - 03/2003
10	Fragile X Syndrome (Martin Bell Syndrome) 02/2022 - 07/2011
4	Congenital central hypoventilation syndrome 11/2012 - 08/2006
3	Intellectual Disability (Idiocy) 02/2022 - 07/2015
3	Autistic Disorder (Autism) 11/2019 - 07/2011
3	Alzheimer Disease (Alzheimer's Disease) 01/2013 - 01/2011
3	Hypoventilation 09/2011 - 10/2006
3	Seizures (Absence Seizure) 09/2011 - 01/2009
2	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2022 - 06/2006
2	Autism Spectrum Disorder 02/2022 - 07/2015
2	Lung Diseases (Lung Disease) 08/2013 - 11/2012
2	Down Syndrome (Down's Syndrome) 07/2011 - 01/2011
2	Nervous System Diseases (Neurological Disorders) 07/2011 - 06/2006
2	Huntington Disease (Huntington's Disease) 04/2009 - 06/2006
1	Rett Syndrome (Rett's Disorder) 01/2022
1	Developmental Disabilities (Developmental Disability) 01/2021
1	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 01/2020
1	Human Influenza (Influenza) 10/2019
1	Neurodevelopmental Disorders 01/2018
1	Narcolepsy 01/2016
1	Apnea 08/2013
1	Ganglioneuroblastoma 09/2011
1	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 09/2011
1	Obesity 09/2011
1	Hypothermia 09/2011
1	Hypothyroidism 09/2011
1	Scoliosis 09/2011
1	Bradycardia 09/2011
1	Parkinson Disease (Parkinson's Disease) 07/2011
1	Epilepsy (Aura) 07/2011
1	Fragile X Tremor Ataxia Syndrome 01/2010
1	Sudden Death 03/2009
1	Obstructive Sleep Apnea 01/2009
1	Hypoxia (Hypoxemia) 01/2009
1	Inflammation (Inflammations) 04/2007
1	Hypoglycemia (Reactive Hypoglycemia) 04/2007
1	Infections 04/2007
1	Hirschsprung Disease (Hirschsprung's Disease) 11/2006
1	Neoplasms (Cancer) 11/2006

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2016 - 03/2003
5	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 04/2007 - 03/2003
4	polyalanineIBA 11/2012 - 08/2006
3	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 02/2022 - 01/2011
3	Fragile X Mental Retardation ProteinIBA 02/2022 - 01/2012
3	DNA (Deoxyribonucleic Acid)IBA 12/2013 - 07/2006
3	Peptides (Polypeptides)IBA 12/2013 - 03/2009
3	Serotonin (5 Hydroxytryptamine)IBA 01/2009 - 08/2007
2	Anesthetics (Anesthetic Agents)IBA 01/2020 - 01/2009
2	Pharmaceutical PreparationsIBA 11/2019 - 01/2018
2	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 12/2013 - 03/2009
2	Amyloid beta-PeptidesIBA 01/2013 - 07/2011
2	Amyloid (Amyloid Fibrils)IBA 07/2011 - 01/2011
2	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 04/2009 - 06/2006
2	Nicotine FDA Link 04/2007 - 07/2006
2	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 11/2006 - 08/2006
1	Indicators and Reagents (Reagents)IBA 02/2022
1	trofinetideIBA 01/2022
1	Insulin-Like PeptidesIBA 01/2022
1	glycyl-prolyl-glutamic acidIBA 01/2022
1	Biological ProductsIBA 01/2021
1	BPN14770IBA 01/2021
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021
1	2-Hydroxypropyl-beta-cyclodextrinIBA 01/2020
1	Metabotropic Glutamate 5 ReceptorIBA 01/2018
1	OrexinsIBA 01/2016
1	Type I Pituitary Adenylate Cyclase-Activating Polypeptide ReceptorsIBA 12/2013
1	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 01/2013
1	gamma-Aminobutyric Acid (GABA)IBA 09/2012
1	GABA-B Receptor AgonistsIBA 09/2012
1	Aminobutyrates (Aminobutyric Acid)IBA 09/2012
1	Growth Hormone (Somatotropin)IBA 09/2011
1	Amino Acids FDA Link 01/2011
1	Messenger RNA (mRNA)IBA 01/2010
1	Lamin Type A (Lamin A)IBA 01/2010
1	LigandsIBA 04/2009
1	NeurturinIBA 04/2009
1	Aspartic Acid (Aspartate)FDA Link 03/2009
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 03/2009
1	Hypnotics and Sedatives (Sedatives)IBA 01/2009
1	Serotonin ReceptorsIBA 01/2009
1	RNA Splice SitesIBA 08/2007
1	Ion Channels (Ion Channel)IBA 04/2007
1	EnzymesIBA 04/2007
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 07/2006
1	3' Untranslated Regions (3' UTR)IBA 07/2006

Therapy/Procedure

2	Therapeutics 07/2015 - 06/2006
1	Cyclotrons 02/2022
1	Anesthesia 01/2020
1	General Anesthesia 01/2020
1	Spinal Injections 01/2020
1	Drug Therapy (Chemotherapy) 11/2019
1	Dental Care 10/2019
1	Artificial Respiration (Mechanical Ventilation) 08/2013
1	Mechanical Ventilators (Ventilator) 11/2012
1	Tonsillectomy 01/2009
1	Adenoidectomy 01/2009